ivf treatment

How does age influence male fertility?

Impact of age on male fertility: hormonal production 

One impact that age can have on male infertility treatment is hormonal production. There is a deregulation of the frequency and production rates of the hormones LH and FSH released by the pituitary gland. Among the consequences is a reduction in the number of Leydig cells in the testicle, inducing a decrease in testosterone production. This phenomenon is observed from the age of 40.

Impact of age on male fertility: sperm production

Age is associated with a reduction in the number of Sertoli cells that produce sperm in the testis. These effects are associated with increased cell death and decreased cell proliferation. Thus, from the age of 50, a man makes 30% fewer sperm each day, significantly impacting his fertility.  

Impact of age on male fertility: sperm parameters

In men aged 50, a decrease in the number of sperm produced is therefore observed. In addition to these effects on male fertility, a reduction in mobility and alterations in the morphology of spermatozoa have been highlighted. Sperm DNA abnormalities are also common in men over 40.

Impact of age on male fertility: benign prostatic hyperplasia

With age, the prostate increases in volume, and this can indeed have an impact on male fertility. This can be associated with a reduction in sperm volume. The prostate participates in the production of seminal fluid, the main component of sperm. This is rich in fructose, proteins, zinc, trace elements, etc., which are essential for the survival of spermatozoa.

Impact of age on male fertility: the evolution of pregnancy

Finally, the last impact that age can have on male fertility concerns the evolution of pregnancy. In men over 40, the fertility clinic power of spermatozoa is impaired. This is associated with a reduced number of embryos reaching the blastocyst stage. The embryo implantation rate is also impaired, reducing pregnancy chances. Contrary to popular belief, the man’s age also influences the couple’s fertility.

Beyond the age of 40, the production of sex hormones, the quantity of sperm produced, and the fertilizing power of sperm are altered. This can lead to a reduction in the chances of embryo implantation. Thus, although there is no such thing as ” male andropause or menopause,” the age of the man can influence the chances of pregnancy.

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